Prospective randomised trial of povidone-iodine, alcohol, and chlorhexidine for prevention of infection associated with central venous and arterial catheters
Page Content
Maki DG, Ringer M, Alvarado CJ. Prospective randomised trial of povidone-iodine, alcohol, and chlorhexidine for prevention of infection associated with central venous and arterial catheters. Lancet. 1991;338(8763):339-343.Randomized controlled trial on a surgical ICU in which 668 catheters were placed with either 10 percent povidone-iodine, 70 percent alcohol, or 2 percent aqueous chlorhexidine disinfection of the site prior to insertion and every other day thereafter. Use of chlorhexidine was associated with the lowest risk or local and bloodstream catheter-related infections.
View article abstract
