Complications of femoral and subclavian venous catheterization in critically ill patients: A randomized controlled trial
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Merrer J, De Jonghe B, Golliot F, et al. Complications of femoral and subclavian venous catheterization in critically ill patients: A randomized controlled trial. Journal of the American Medical Association. 2001;286(6):700-707.Randomized controlled trial in 289 adults requiring a first central venous catheter, randomized to femoral or subclavian site. The femoral site was associated with a higher risk of infectious and thrombotic complications.