A controlled trial of scheduled replacement of central venous and pulmonary-artery catheters
Page Content
Cobb DK, High KP, Sawyer RG, et al. A controlled trial of scheduled replacement of central venous and pulmonary-artery catheters. New England Journal of Medicine. Oct 1992;327(15):1062-1068.Controlled trial in adult ICU patients requiring central venous or pulmonary artery catheters for more than three days. Guide wire exchange was associated with an increased risk of bloodstream infection. Reinsertion at a new site was associated with an increased risk of mechanical complications. Replacement at three days did not reduce the risk of infection.
