Author in the Room: Cardiovascular Disease in Hypertensive Persons

May 2011 Author in the Room® Teleconference


Authors: Lydia A Bazzano, MD, PhD, and Angela M. Thompson


Article: "Antihypertensive Treatment and Secondary Prevention of Cardiovascular Disease Events Among Persons Without Hypertension: A Meta-analysis"

Summary Points:
  • Cardiovascular disease (CVD) risk increases beginning at systolic blood pressure levels of 115 mmHg and the use of antihypertensive medications among patients with a history of CVD or diabetes and without hypertension has been debated.
  • Among patients with clinical history of  CVD but with blood pressure lower than 140/90 mmHg, antihypertensive treatment was associated with decreased risk of stroke, congestive heart failure, composite CVD events, and all-cause mortality.  
  • Additional randomized trial data are necessary to assess these outcomes in patients without CVD events.


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