Please wait while you are being redirected ...
This site is best viewed with Internet Explorer version 8 or greater. Check your browser compatibility mode if you are using Internet Explorer version 8 or greater.
Log In / Register
Newsletter Sign Up
Newsletter Sign Up
Sign up for IHI's Email Services
Improving Health and Health Care Worldwide
Engage with IHI
Vision, Mission, Values
Science of Improvement
How to Get Involved
In the News
All Topics A-Z
Quality, Cost, and Value
Triple Aim for Populations
IHI National Forum
Passport to IHI Training
WIHI Audio Program
Certified Professional in Patient Safety (CPPS)
IHI Open School
How to Improve
IHI White Papers
Audio and Video
Engage with IHI
Engage with IHI Overview
143 items found
Use SHIFT+ENTER to open the menu (new window).
Methods for Reducing Sepsis Mortality in Emergency Departments and Inpatient Units
North Shore-LIJ Health System (now Northwell Health) launched a strategic partnership with the Institute for Healthcare Improvement to accelerate the pace of sepsis improvement, focusing initially on sepsis recognition and treatment in emergency departments (EDs). The health system reduced overall sepsis mortality by approximately 50 percent in a six-year period and increased compliance with sepsis resuscitation bundle elements in the EDs and inpatient units in 11 acute care hospitals.
Understanding Bundles: An IHI Faculty Conversation
IHI faculty for the Rethinking Critical Care seminar discuss and try to clarify some important and often misunderstood points about implementing care bundles (such as the Ventilator Bundle and the Central Line Bundle).
Remeasure Lactate If Initial Lactate Was Elevated Goal
Compliance with this element in the Severe Sepsis Bundles (as part of the 6-Hour Septic Shock Bundle) is defined as the percent of patients following septic shock or lactate ≥4 mmol/L (36 mg/dl) identification for whom the lactate was repeated during the first 6 hours after presentation.
Compliance with Severe Sepsis Bundles (with the Goal of Reducing Mortality)
Measuring compliance with the Severe Sepsis Bundles will allow your team to judge how well your institution is performing in achieving the goal of 100 percent compliance with all Severe Sepsis Bundles elements.
Severe Sepsis Bundles
The Severe Sepsis Bundles include the Severe Sepsis 3-Hour Rescuscitation Bundle and the 6-Hour Septic Shock Bundle. The Severe Sepsis Bundles have been revised in conjunction with the updated 2012 International Guidelines for Management of Severe Sepsis and Septic Shock.
Reliability: Severe Sepsis Bundles
The percent of cases of severe sepsis and/or septic shock for whom all applicable Severe Sepsis Bundles elements are completed.
WIHI: A Partnership to Reduce Deaths from Sepsis
January 24, 2013 | This WIHI explores how North Shore–Long Island Jewish Health System has reduced its sepsis mortality rate significantly, and what others can learn from their progress.
Using Care Bundles to Improve Health Care Quality
This IHI white paper describes the history, theory of change, design concepts, and outcomes associated with the development and use of bundles — a small set of evidence-based interventions for a defined patient population and care setting — and reflects on learning over the past decade.
Passport Exclusive: The Sepsis Bundle
In this video, IHI faculty member Dr. Sean Townsend gives an overview of the Sepsis Bundle and how to get started on this work.
Glycemic Control Goal
Current literature suggests appropriate glycemic control in the ICU reduces morbidity and overall mortality in the critically ill.
Renal effects of norepinephrine used to treat septic shock patients
This study finds that norepinephrine does not have deleterious effects, and may have beneficial effects, on renal function in patients with severe septic shock.
First Steps and Measures to Reduce Sepsis Mortality
University of Rochester/Strong Health (Rochester, New York, USA) implemented the 2004 Surviving Sepsis Campaign clinical practice guidelines, using a previous iteration of the Sepsis Bundle to decrease septic patients’ overall mortality.
IHI Contributing to Bold International Campaign to Dramatically Reduce Mortality from Sepsis
A team of clinicians and quality leaders from IHI is helping to drive forward the work of a remarkable international partnership, dedicated to reducing the global toll of sepsis — a deadly syndrome that kills more people in a year in North America than breast cancer, lung cancer, and colon cancer combined.
Sepsis Care Enters New Era
They are principles key to transforming health care: teamwork and adherence to standards. In a demonstration of exactly these qualities, a worldwide movement, the Surviving Sepsis Campaign, in partnership with the Institute for Healthcare Improvement, is breaking new ground in a battle against an elusive foe.
Sepsis: Putting the Pieces Together
Baptist Memorial Hospital (Memphis, Tennessee, USA) describes their work to reduce mortality from sepsis in their intensive care settings.
Defeating Sepsis: 25 Percent by 2009
The goal of the Surviving Sepsis Campaign is to reduce the risk of dying from sepsis by 25 percent by 2009. Forty-one countries are participating in this international collaborative effort to improve the treatment of sepsis and reduce the high mortality rate associated with the condition.
Early Goal Directed Therapy Reduces Sepsis Complications and Mortality
At PeaceHealth/St. Joseph Hospital (Bellingham, Washington, USA), a partnership between the ICU and the ED, as well as ongoing surveillance and feedback to individual providers, reduced mortality related to severe sepsis and septic shock from 41 to 50 percent in the two months prior to implementation to an average of 17 percent after implementation of the Sepsis Resuscitation and Sepsis Management Bundles.
Central Venous Oxygen Saturation Goal
Compliance with this element of the Severe Sepsis Bundles (as part of the 6-Hour Septic Shock Bundle) is defined as the percent of patients following septic shock or lactate >4 mmol/L (36 mg/dl) identification for whom the ScvO2 is >70 percent (or SvO2 is >65 percent) within 6 hours of presentation time.
Central Venous Pressure Goal
Compliance with this element of the Severe Sepsis Bundles (as part of the 6-Hour Septic Shock Bundle) is defined as the percent of patients for whom a CVP goal of >8 mm Hg was achieved within 6 hours following septic shock or lactate ≥4 mmol/L (36 mg/dl) identification.
Timing of Antibiotics
This measure is a component of the Severe Sepsis Bundles (as part of the Severe Sepsis 3-Hour Resuscitation Bundle) and is defined as the median time in minutes to the administration of broad-spectrum antibiotic(s) from the time of presentation with severe sepsis.
Timing of Blood Cultures
Compliance with this element of the Severe Sepsis Bundles (as part of the Severe Sepsis 3-Hour Resuscitation Bundle) is defined as the percent of patients presenting with severe sepsis and/or septic shock who had blood cultures collected prior to broad-spectrum antibiotic administration.
Sepsis Median Plateau Pressure Calculation Tool
Use this optional tool for easy calculation of the median inspiratory plateau pressure for a mecahnically ventilated patient with severe sepsis within the first 24 hours of presentation, then enter this data in the Sepsis Individual Chart Measurement Tool.
American College of Emergency Physicians
The American College of Emergency Physicians (ACEP) represents more than 22,000 members and is the oldest and largest emergency medicine organization.
ARDS Clinical Network
The ARDS Clinical Network was established in 1994 to hasten the development of effective therapies for Acute Respiratory Distress Syndrome (ARDS).
The International Sepsis Forum (ISF)
The International Sepsis Forum (ISF) is a collaborative effort between industry and academia that focuses solely on management of patients with severe sepsis.