Institute for Healthcare Improvement
Cambridge, Massachusetts, USA
Last updated: March 2012
How to cite this document:
How-to Guide: Prevent Central Line-Associated Bloodstream Infections. Cambridge, MA: Institute for Healthcare Improvement; 2012. (Available at
This How-to Guide describes key evidence-based care components of the IHI Central Line Bundle which has been linked to prevention of central line-associated bloodstream infections, describes how to implement these interventions, and recommends measures to gauge improvement. The guide was initially developed as part of IHI's
5 Million Lives Campaign.