Landrigan CP, Parry GJ, Bones CB, Hackbarth AD, Goldmann DA, Sharek PJ. Temporal trends in rates of patient harm resulting from medical care. New England Journal of Medicine. 2010 Nov; 363(22):2124-2134.
A retrospective study of a stratified random sample of 10 hospitals in North Carolina. A total of 100 admissions per quarter from January 2002 through December 2007 were reviewed in random order by teams of nurse reviewers from within and outside the hospitals using the IHI Global Trigger Tool for Measuring Adverse Events. The study finds that harms remain common, the IHI Global Trigger Tool is a reliable instrument for detecting harm, and further efforts are needed to translate effective safety interventions into routine practice and to monitor health care safety over time. [Read additional perspective from the study authors.]