Sandora TJ, Goldmann DA. Preventing lethal hospital outbreaks of antibiotic-resistant bacteria. New England Journal of Medicine. 2012 Dec;367(23):2168-2170.
Overuse of antibiotics promotes resistance in individual hospitals and contributes to the global emergence and spread of multidrug-resistant organisms (MDROs). The authors argue that the spread of these dangerous, sometimes lethal, outbreaks can be curtailed if hospitals take appropriate action, starting with reliable adherence to basic, evidence-based infection control practices and lessening the overuse of antibiotics. They offer a small set of interventions aimed at reducing exposure to antibiotics.