Classen DC, Lloyd RC, Provost L, Griffin FA, Resar R. Development and evaluation of the Institute for Healthcare Improvement Global Trigger Tool. Journal of Patient Safety. 2008 Sep;4(3):169-177.
This article reports on a study to develop and evaluate a more robust approach for the detection of adverse events in hospital patients using an enhanced Institute for Healthcare Improvement Global Trigger Tool methodology. The authors conclude that the retrospective record review approach with a two-stage review process, when used with trained reviewers, achieves high levels of agreement on the presence and severity of adverse events.