Meisel M, Meisel S. Best-practice protocols: Reducing harm from high-alert medications. Nursing Management. 2007 July;38(7):31-39.This second article in a series describes reducing harm to patients from high-alert medications by reviewing a case study on the importance of postoperative monitoring of opioid-naive patients who are receiving narcotics. The series presents a nursing management perspective on the six interventions recommended by the Institute for Healthcare Improvement as part of its 5 Million Lives Campaign to protect patients from five million incidents of medical harm over a two-year period.