Quantitation of CD4 cells was the first effective predictor of HIV progression, and is still the best predictor for persons with HIV-2 or HIV-1 variants that cannot be accurately quantitated using viral load assays. The CD4 cell count is important in determining the staging of HIV disease and for indicating the need for prophylaxis against opportunistic pathogens, and continues to be used to assist in decisions regarding initiation or adjustment of ARV treatment. CD4 cell count assessment is recommended every three to four months.

Formula:  The number of pediatric patients (birth to 13 years) with at least one HIV primary care visit in the past 12 months who have also had a CD4 test lasting the past four months, divided by the total number of HIV/AIDS pediatric patients (birth to 13 years) with at least one HIV primary care visit in the past 12 months. Multiply by 100 to calculate percent.

For further explanation of this indicator and/or criteria for exclusions, please review indicator definitions available on the National HIVQUAL Project’s website.

100 percent of pediatric patients will have a CD4 count every four months.

At the end of each month (or at the frequency indicated by your improvement initiative), count the number of pediatric patients, birth to 13 years, with at least one HIV primary care visit in the past 12 months who have also had a CD4 count in the last four months.  Divide by the total number of pediatric patients, birth to 13 years, with at least one HIV primary care visit in the past 12 months. Multiply by 100 to calculate percent.