Quantitation of CD4 cells, the first effective predictor of HIV progression, is still the best predictor for persons with HIV-2 or HIV-1 variants that cannot be accurately quantitated using viral load assays. The CD4 cell count plays a vital role in determining the staging of HIV disease and indicating the need for prophylaxis against opportunistic pathogens. It continues to be used to assist in decisions regarding initiation or adjustment of antiretroviral (ARV) treatment. CD4 cell count assessment is recommended every three to four months.

Formula:  The number of patients/clients with at least one HIV primary care visit in the past 12 months who also had a CD4 count test taken during the last 4 months, divided by the total number of HIV/AIDS patients/clients with at least one HIV primary care visit in the past 12 months.  Multiply by 100 to calculate percent.

Greater than 90 percent of patients/clients will have a CD4 count every 4 months.

At the end of each month (or at the frequency indicated by your improvement initiative), count the number of patients with at least one HIV primary care visit in the past 12 months who have also had a CD4 count in the last 4 months.  Divide by the total number of patients/clients with at least one HIV primary care visit in the past 12 months. Multiply by 100 to calculate percent. 

The National HIVQUAL Project’s Minimum Sample Table will help you determine the number of records to include in your sample. The Research Randomizer can generate a random number series to help you select which records to review.