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Systemic inflammatory response and progression to severe sepsis in critically ill infected patients
Alberti C, Brun-Buisson C, Chevret S, et al. Systemic inflammatory response and progression to severe sepsis in critically ill infected patients. American Journal of Respiratory and Critical Care Medicine. Nov 2004.

This article describes a study which tried to examine the incidence of and risk factors for worsening sepsis in infected patients.  The study concludes that about one quarter of patients with infection/sepsis have their condition worsen to severe sepsis or shock.

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