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Plasma cortisol levels before and during “low-dose” hydrocortisone therapy and their relationship to hemodynamic improvement in patients with septic shock
Oppert M, Reinicke A, Gräf KJ, et al. Plasma cortisol levels before and during “low-dose” hydrocortisone therapy and their relationship to hemodynamic improvement in patients with septic shock. Intensive Care Medicine. 2000;26(12):1747–1755.

This study assesses the effect of endogenous steroid production on both the clinical course of septic shock and the need for catecholamine administration.



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