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Efficacy of adequate early antibiotic therapy in ventilator-associated pneumonia: Influence of disease severity
Clec'h C, Timsit JF, De Lassence A. Efficacy of adequate early antibiotic therapy in ventilator-associated pneumonia: Influence of disease severity. Intensive Care Medicine. 2004;30(7):1327-33.

This prospective clinical study suggests that for certain patients, inadequate antimicrobial therapy can lead to an increase in mortality. 



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