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A trial of goal-oriented hemodynamic therapy in critically ill patients: SvO2 Collaborative Group
Gattinoni L, Brazzi L, Pelosi P, et al. A trial of goal-oriented hemodynamic therapy in critically ill patients. New England Journal of Medicine. 1995;333(16):1025–1032.

An study detailing whether hemodynamic therapy to raise the cardiac index and oxygen delivery to supranormal may improve outcomes in critically ill patients.

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