Reduction in the incidence of type 2 diabetes with lifestyle intervention or metformin
Knowler WC, Barrett-Connor E, Fowler SE, et al. Reduction in the incidence of type 2 diabetes with lifestyle intervention or metformin. New England Journal of Medicine. 2002;34(6):393-403.
This paper points out the effectiveness of intensive behavior change in lifestyle in delaying (or preventing) the onset of type 2 diabetes. It also has relevance to the management of patients with established type 2 diabetes.
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