ADEs can be significantly reduced by implementation of known safety practices, such as unit dosing, standardization of prescribing rules, computerized drug profiling in the pharmacy, standardized dosing regimens, and redesign of medication processes using Failure Modes and Effects Analysis and proven human factors principles.
In addition, developing a culture of safety through the use of briefings, communication techniques and leadership involvement leads to an environment where staff more readily prevent, detect, and mitigate patient harm. IHI has been working with committed organizations for many years on ADE reduction, many of whom have realized a tenfold decrease or greater.